Advancements in the Management of Gynecological Cancers: ESMO 2024 - Episode 2

Key Findings from the PRIMA Trial: Niraparib in 1L Maintenance for Advanced Ovarian Cancer

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Panelists discuss optimal durations for PARP inhibitor maintenance therapy in ovarian cancer, exploring how long patients are typically kept on PARPi in both first-line and second-line maintenance settings.

Video content above is prompted by the following:

  • Briefly comment on key findings and final OS data from the PRIMA trial, evaluating niraparib 1L maintenance therapy in newly diagnosed advanced ovarian cancer.
  • What implications do these findings have and what impact may they have on the treatment paradigm for ovarian cancer?
  • What new insights can be drawn about long-term responders to maintenance niraparib from the recent subanalysis of the GEICO-88R study?