Multidisciplinary Collaboration to Improve Early Recognition and Care For CA-LEMS

In this concluding segment, the panel emphasize the essential role of coordinated care between oncologists and neurologists in improving outcomes for patients with cancer-associated Lambert-Eaton myasthenic syndrome (LEMS). They underscore the value of building regional referral networks and identifying centers with dedicated paraneoplastic neurology programs, such as the clinic at Northwestern, which can serve as specialized resources for complex diagnostic evaluations. They highlight the importance of early engagement with neurology—ideally in a proactive, anticipatory capacity—to streamline diagnosis and optimize management. Expert faculty further advises clinicians to maintain a high index of suspicion in patients with small cell lung cancer or other neuroendocrine tumors and to incorporate early neurologic screening tools, voltage-gated calcium channel antibody testing, and EMG/nerve conduction studies with explicit evaluation for LEMS. The discussion reinforces that early, structured collaboration and clear referral pathways are key to timely recognition and effective treatment of this rare paraneoplastic syndrome.