Advancements in the Management of Gynecological Cancers: ESMO 2024 - Episode 10

Biomarker Testing in Advanced Endometrial Cancer: Approach, Key Markers, and Impact on Treatment Decisions

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Panelists discuss their approach to biomarker testing in advanced endometrial cancer, including the timing and types of testing performed, the specific biomarkers assessed (such as mismatch repair/microsatellite instability, POLE, and TP53), and how these results inform treatment decisions.

Video content above is prompted by the following:

How do you typically approach biomarker testing for advanced endometrial cancer?

  • When do you test/retest, and what type of testing do you perform?
  • Which biomarkers do you generally access (eg, mismatch repair/microsatellite instability, POLE, TP53, etc) and how do results help guide your treatment approach?