Advancements in the Management of Gynecological Cancers: ESMO 2024 - Episode 4

Emerging Combinations in Maintenance Therapy for Ovarian Cancer

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Panelists discuss how emerging maintenance strategies for advanced/metastatic disease increasingly focus on novel combination approaches, including immunotherapy combinations with PARP inhibitors (rucaparib + nivolumab), anti-angiogenic agents (atezolizumab + bevacizumab), and dual targeted therapy (olaparib + cediranib), with ongoing evaluation of optimal patient selection and sequencing in the treatment paradigm.

Video content above is prompted by the following:

What new maintenance strategies (eg, immunotherapy combination therapy or hormonal maintenance therapy) are being explored for advanced/metastatic disease?

  • Rucaparib + nivolumab
  • Atezolizumab + bevacizumab
  • Olaparib + cediranib
  • Where do these fit in the treatment paradigm?
  • In which patients may you consider these combination approaches?