Advancements in the Management of Gynecological Cancers: ESMO 2024 - Episode 1

Approaching Biomarker Testing and Frontline Maintenance Therapy for Advanced Ovarian Cancer

, , , ,

Panelists discuss frontline maintenance therapies for advanced ovarian cancer, focusing on the impact of BRCA and HRD statuses on treatment selection and the choice between combination therapy (PARPi + bev) and monotherapy.

Video content above is prompted by the following:

  • How do you typically approach biomarker testing for advanced ovarian cancer?
  • When do you test and what type of testing do you perform?
  • Which biomarkers do you generally access (e.g., BRCA1/2, HRD, etc) and how do results help guide your treatment approach?
  • Briefly review frontline maintenance therapy options for advanced ovarian cancer and discuss key factors that drive your selection among available therapies.
  • How do BRCA and HRD statuses influence your choice of maintenance therapy?
  • When may you opt for a combination (PARPi + bev) vs monotherapy approach?