First AD

Second AD

Radiation and Targeted Therapies for Progressive pLGG

Please briefly describe the various treatment options that might be considered in R/R pLGG

Clinical

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Insights

Insights is an expert interview video series of leading oncologists that provides in-depth reports and feature segments profiling leaders in a range of oncology disciplines, including breast cancer, lung cancer, gastrointestinal cancers, genitourinary cancers, gynecologic cancers, and hematologic malignancies. Most episodes feature 2 clinicians discussing the latest oncology advances in clinical practice. 

Video Series

Novel Breakthroughs in Management of Pediatric Low-Grade Glioma (pLGG)

The panel of medical experts examines the roles of radiation therapy and targeted therapies in the management of progressive pediatric low-grade gliomas (pLGG).

Overview of pLGG presentation and categorization

Molecular Characterization of pLGG

Less Common Molecular Alterations in pLGG and Testing Recommendations

Standard of care for frontline treatment of non-V600E-specific pLGG tumors

Ongoing clinical trials for frontline treatment of non-V600E-specific pLGG tumors

Current Treatment of Patients with NF1 pLGG

Standard of Care Pptions Specific for Frontline Treatment of BRAF V600E-Mutated pLGG

Treatment Considerations for Progressive pLGG

The Role of Tovorafenib in Treatment of Progressive pLGG

Clinical Trials to Increase Treatment Options in the Progressive Setting

Clinical scenario 1 - BRAFKIAA-1549 fusion

Alternatives and Considerations for Clinical Scenario 1

Clinical Scenario 2 - BRAFV600E

Potential Adverse Events With Targeted Therapies

Clinical Insights: Looking Forward for pLGG