Identifying Surgical Candidates in cSCC

Panelists explain that surgery remains the preferred option for most resectable high-risk cutaneous squamous cell carcinoma (cSCC). Ideal candidates are those with localized disease, good performance status, and lesions that can be excised with functional and aesthetic preservation.

They emphasize the importance of early referral to head and neck or reconstructive surgeons for complex or recurrent cases, where achieving clear margins is critical. Multidisciplinary consultation can determine whether surgery alone suffices or if adjuvant treatment is warranted.

The discussion reinforces that integrating surgery early within a coordinated care model maximizes both local control and quality of life for patients.