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ESMO 2024: Treatment of uHCC - Episode 17

Future Directions for Treating uHCC: Triplet Therapy, Epigenetic Therapy, Cytotoxic Agents, and Antibody-Drug Conjugates (ADCs

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Panelists discuss how ongoing trials and investigational agents, including the Checkmate 9DW study, could significantly influence future treatment approaches for unresectable hepatocellular carcinoma .

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    EP. 1: Current Treatment Landscape – difference between unresectable (uHCC) and metastatic (mHCC)
    EP. 2: Treatment Decisions Based on BLCL Stage
    EP. 3: Current Treatment in First Line – IO + TKI or IO + IO
    EP. 4: Use of monotherapy (IO or TKI) or localized treatment in First Line
    EP. 5: EMERALD-1 Study Results
    EP. 6: Discussion and Summary
    EP. 7: LEAP-012 Study Results
    EP. 8: Discussion of LEAP-012 and EMERALD-1 Study Results and Appropriate Sequencing
    EP. 9: ImBRAVE 050 Study Results and Discussion Around Who is a High-Risk Patient
    EP. 10: Choosing Second-Line Therapies: Considering First Line Therapy Received
    EP. 11: Discussion of CELESTIAL Trial and Second-Line Treatment in Japan
    EP. 12: CELESTIAL Sub-Group Discussion
    EP. 13: Discussion of RESORCE Trial
    EP. 14: Real-World Treatment Data from the Phase 4 STELLAR Trial
    EP. 15: Importance of Real-World Data in Supporting Treatment Options
    EP. 16: CheckMate 9DW Study Results and Use of Ipiimumab/Nivolumab in First- and Second-Line Treatment
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    EP. 17: Future Directions for Treating uHCC: Triplet Therapy, Epigenetic Therapy, Cytotoxic Agents, and Antibody-Drug Conjugates (ADCs

    Video content above is prompted by the following:

    Dr Finn to group (Iif time allows): Are there other trials or investigational agents that for which you are waiting for updates that could potentially impact affect how unresectable hepatocellular carcinoma uHCC is treated?

    • Any additional thoughts on findings from Checkmate 9DW?

    Related Content:

    ESMO 2024: Treatment of uHCC
    CheckMate 9DW Study Results and Use of Ipiimumab/Nivolumab in First- and Second-Line Treatment
    Importance of Real-World Data in Supporting Treatment Options
    Discussion of RESORCE Trial
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