Advancing Synovial Sarcoma Care: Exploring Innovations in Targeted Therapies - Episode 9

Best Practices for HLA and MAGE-A4 Testing

A panelist discusses how the main challenges in MAGE-A4 testing include optimizing the timing of both human leukocyte antigen (HLA) and MAGE-A4 expression testing, establishing standardized testing protocols across institutions, and ensuring adequate tissue availability for testing, while recommending early screening at diagnosis or first relapse to allow sufficient time for treatment planning if patients become eligible.

Video content above is prompted by the following:

  • When testing for MAGE-A4 expression, what challenges do you anticipate in identifying eligible patients?
  • When are you testing for HLA and MAGE-A4, and what do you recommend to your colleagues?