ASCO 2024: Updates in the Treatment of Advanced Renal Cell Carcinoma - Episode 1

Treatment Selection in the Frontline Setting of Advanced Clear Cell RCC

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Dr. Pedro Barata, MD, MSc, provides an overview of advanced clear cell renal cell carcinoma (RCC), discussing its typical presentation, the role of systemic therapies, and summarizing the first-line treatment options available for this condition.

  1. Please give an introduction of advanced clear cell RCC, including typical disease presentation and the role of systemic therapies in treatment. 
    1. Please give a summary of the first-line treatment options for advanced clear cell RCC
    2. How do you approach treatment selection (IO+IO vs. IO+TKI, etc.) in the frontline setting?
  2. Are there any key patient characteristics that inform this decision?