ASCO 2024: Updates in the Treatment of Advanced Renal Cell Carcinoma - Episode 3

Dr Xu Reviews Data from the CLEAR Trial and Recent Analyses at ASCO 2024 - Lenvatinib + Pembrolizumab in Frontline Advanced RCC

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Wenxin (Vincent) Xu, MD, reviews recent analyses from the CLEAR study, which evaluated the combination of lenvatinib and pembrolizumab as a frontline treatment for advanced renal cell carcinoma (RCC).

  1. Please discuss recent analyses from the CLEAR study, evaluating lenvatinib + pembro in frontline advanced RCC. 
    1. Efficacy by baseline tumor size (Grunwald, et al. ASCO GU 2024. Abstract 364)
    2. Biomarker analysis (Motzer et al. ASCO 2024 Abstract 4504)
    3. Network meta-analysis– len + pembro vs other 1L treatments in advanced RCC (Grunwald, et al. ASCO GU 2024. Abstract 482)