Clinical Considerations for Immuno-oncology (IO) Sequencing in Advanced Endometrial Cancer - Episode 13
Impact of Quality of Life Considerations in Treatment Choices for Patients With Advanced EC
Panelists discuss how considering a patient's quality of life (QOL)—including treatment adverse effects, functional status, mental health, and the burden of care—is essential in making treatment decisions, with shared decision-making ensuring that therapeutic choices align with the patient's values and QOL priorities.
Summary for Physicians:
When making treatment decisions, it is essential to consider the impact on a patient's QOL. Key factors include the potential adverse effects of treatments, such as fatigue, gastrointestinal issues, or immune-related adverse events, which can significantly affect a patient's daily functioning and overall well-being. The treatment's ability to maintain or improve a patient's functional status, independence, and mental health is also critical. Additionally, the burden of frequent clinic visits, hospitalizations, or the need for complex care regimens should be considered, as these can impact both physical and emotional QOL. In advanced cancer settings, balancing the effectiveness of treatment with the patient's preferences for symptom management, life expectancy, and maintaining QOL is essential in guiding therapeutic choices. Shared decision-making with the patient, taking their personal values and goals into account, can help ensure a treatment plan that aligns with their QOL priorities.
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