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Genomic Testing in Breast Cancer: Clinical Applications and Best Practices - Episode 2

Genomic Testing in Early-Stage Breast Cancer: Institutional and Multidisciplinary Perspectives

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Discover essential insights on breast cancer awareness, prevention, and treatment options to empower your health journey.

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    Approaches to Genomic Testing Implementation

    Main Discussion Topics:

    • Multidisciplinary approach to genomic testing decisions in early-stage breast cancer
    • Timing considerations for test ordering (presurgical core biopsy vs postsurgical specimen)
    • Communication approaches with patients regarding testing and results

    Key Points for Physicians:

    • Genomic testing decisions benefit from multidisciplinary tumor board input involving surgeons, medical oncologists, and pathologists.
    • Testing on core biopsy specimens can reduce the time to treatment decisions by 2 to 3 weeks.
    • Testing may be unnecessary if a patient has comorbidities precluding chemotherapy or has already declined chemotherapy.

    Notable Insights:

    • Surgeons often order the genomic tests, but medical oncologists typically use the information to guide treatment decisions.
    • Reducing time between diagnosis and treatment plan development addresses patients’ key concerns: “Why did I get this?” and “Will I need chemotherapy?”

    Clinical Significance: Effective implementation of genomic testing requires thoughtful coordination between surgical and medical oncology teams, with consideration for patient preferences, and timing that can significantly improve the treatment planning process..

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