OncLive SOSS

ASH 2024: Global Updates in the Management of Chronic Lymphocytic Leukemia - Episode 9

Exploring Novel BCL2i and BTKi Combinations in Frontline CLL Therapy

February 3, 2025

Carsten Niemann, MD, PhD, Arnon Kater, MD, PhD, Othman Al-Sawaf, MD, John F. Seymour, MBBS, FRACP, PhD

Panelists discuss the ongoing trials evaluating other BCL2i/BTKi combination approaches.

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EP. 1: Recent Guideline Updates in the Frontline Management of CLL

EP. 2: Tailoring Treatment Approaches for Fit vs Unfit CLL Patients

EP. 3: Implications of ESMO Guidelines for IGHV-Mutated vs Unmutated CLL Patients

EP. 4: Time-Limited Therapy with Venetoclax-Obinutuzumab: Rationale and Data

EP. 5: Clinical Insights and Real-World Evidence

EP. 6: Doublet Therapy With Venetoclax-Ibrutinib: Data and Guidelines

EP. 7: Comparing Venetoclax-Ibrutinib, Venetoclax-Obinutuzumab, and BTKi Options

EP. 8: Managing CLL with TP53 Mutation or del(17p): Guidelines and Strategies

EP. 9: Exploring Novel BCL2i and BTKi Combinations in Frontline CLL Therapy

EP. 10: Relapse After Venetoclax-Based Therapy: Early vs Late Management

EP. 11: Progression on BTK Inhibitors: Treatment Options and Considerations

EP. 12: Emerging Agents and Future Strategies in Relapsed/Refractory CLL

EP. 13: Reflections and Future Directions in CLL Management

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Briefly comment on ongoing trials evaluating other BCL2i/BTKi combination approaches and the potential role of these in the front-line setting.

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