Current Treatment Standards in Metastatic Uveal Melanoma

Andrea Forschner, MD, and Shaheer Ahmad Khan, DO, review current therapeutic standards in metastatic uveal melanoma, emphasizing the unique biology of this rare malignancy and its predominantly hepatic pattern of spread. They highlight available systemic options, including immunotherapies and targeted approaches, and note the limitations in response rates compared with cutaneous melanoma. Forschner and Khan also address ongoing challenges in optimizing patient outcomes and the need for more effective, liver-directed treatment strategies.