Lauren M. Green

Articles

CO-1686 Continues to Show Promising Results in Treatment-Resistant NSCLC

June 1st 2014

The third-generation EGFR inhibitor CO-1686 continues to demonstrate promising activity in patients with nonâ€“small cell lung cancer (NSCLC) who developed resistance after prior treatment with an EGFR tyrosine kinase inhibitor (TKI).

Early Palliative Care for Caregivers Improves Their Wellbeing, Too

May 31st 2014

A phone-based intervention that offers practical tools to help family caregivers support their loved one with advanced cancer-as well as emphasizing the importance of maintaining a healthy lifestyle themselves-resulted in less caregiver depression and better quality of life, according to the findings of a new study presented May 30 at the 50th Annual ASCO Meeting in Chicago.

Doxepin Rinse Relieves Pain in Patients With Radiation-Related Oral Mucositis

May 21st 2014

Doxepin rinse may prove to be a viable option for the relief of pain associated with oral mucositis (OM) in patients with head and neck cancers, according to findings of a phase III trial.

For Premenopausal Women With ER-Positive Disease, Obesity Is a Major Risk Factor in Breast Cancer Mortality

May 14th 2014

Obesity significantly increases the risk of dying of breast cancer in premenopausal women with ER-positive early disease.

New PER Conference Debuts With Format Aimed at Pressing Clinical Issues

May 1st 2014

Leading experts in the rapidly evolving field of lung cancer treatment assembled to offer their perspectives on the latest research and provide clinical insights for practitioners dealing with challenging cases.

Breast Cancer Patients Fare Worse When Adjuvant Chemotherapy Is Delayed

April 4th 2014

Breast cancer patients whose chemotherapy is initiated >60 days following surgery experience worse survival outcomes

FDA Panel Unanimously Recommends New DNA Stool Test

March 27th 2014

The FDA's Molecular and Clinical Genetics advisory committee has unanimously supported the safety, efficacy, and positive risk-benefit profile of the noninvasive stool-based DNA test Cologuard in a 10-0 vote.

What's Ahead for BRCA Genetic Testing and Counseling?

March 8th 2014

The US Supreme Court's landmark decision last June, mandating that an individual's genes cannot be patented, transformed the genetic testing landscape and opened the marketplace to a host of new and complicated testing options.

One in Five Cancer Trials End Too Early, but GU Studies Not More Likely

January 28th 2014

The premature termination of clinical trials in the oncology setting is a problem that continues to vex researchers.

Studies Demonstrate Potential of Immunomodulation as Therapeutic Target in Gynecologic Cancers

January 17th 2014

The renaissance in immunology is already affecting treatment paradigms for a variety of gynecologic cancers, and the impact is only likely to expand.

PARP Inhibitors Reemerge as Treatment for Serous Ovarian Cancer

December 31st 2013

The genomic instability inherent in serous ovarian cancer poses treatment challenges, but it also represents a target which can be exploited through the use of PARP inhibitors

Providing Coordinated, Patient-Centered Survivorship Care

November 6th 2013

The growing number of survivors of cancer in the United States today-nearly 14 million strong and rising-is indeed a cause for celebration.

Managing mTOR Inhibitor Side Effects in Breast Cancer

November 4th 2013

Selecting the optimal treatment for postmenopausal patients with hormone receptor (HR)-positive metastatic breast cancer (MBC) remains a challenge, given a preponderance of data for several approved therapeutics

A Clear and Present Danger: Awareness, Vigilance Remain Key to Safe Chemotherapy Handling

September 27th 2013

It has been nearly a decade since the National Institute on Occupational Safety and Health (NIOSH) issued its seminal 2004 Alert warning healthcare workers about the risks of working with hazardous drugs

Ginseng Improves Cancer-Related Fatigue in Phase III Trial

September 3rd 2013

A multisite, randomized, double-blind trial evaluating the fatigue-ameliorating properties of American ginseng in cancer patients and recent survivors has found the herb to be helpful in reducing some aspects of CRF, with the benefit strongest among patients currently in treatment.

More Genetic Screening Needed for African-American Breast Cancer Patients

August 15th 2013

One in five African-American women with breast cancer carries an abnormality in at least one gene associated with breast cancer susceptibility.

Most Survivors Not Discussing Psychosocial Needs With Providers

July 16th 2013

Less than one-third of all survivors of adult cancers in the United States had discussions with their healthcare providers about their psychosocial care needs.

Genetic Alterations Linked to Poorer Prostate Cancer Prognosis

July 16th 2013

Alterations in the chromosomes of two genes have been implicated in an increased risk of prostate cancer mortality, and the discovery holds promise for distinguishing which patients are candidates for more aggressive therapy.

E-tools Can Improve Patient Education Efforts and Symptom Management

June 25th 2013

Creating more opportunities for patients to report their symptoms and treatment experiences is essential to providing patient-centered care.

CRPC Challenge: Sequencing Chemotherapy With New Agents

June 12th 2013

Challenges remain regarding the mechanisms of docetaxel resistance, whether combination studies continue to make sense, and how the sequencing of docetaxel may impact toxicity and efficacy.