ASH 2024: Updates in the Treatment of CLL - Episode 10

Treatment Sequencing in R/R CLL: Optimizing Strategies and Clinical Insights From ASH 2024 Real-World Data

Panelists discuss how treatment sequencing in chronic lymphocytic leukemia (CLL) should be personalized based on prior therapy responses and resistance patterns, with emerging real-world data from ASH 2024 informing decisions about re-treatment with drug classes and treatment holidays, while considering factors like durability of previous responses and the timing of molecular resistance.

Video content above is prompted by the following:

  • What is your treatment sequencing approach? Is there an optimal treatment sequence?
  • Please share your clinical treatment sequencing management and results from the ASH 2024 abstract P5114.
  • Feel free to share any similarities or differences in practice in treatment sequencing.
  • When do you consider re-treatment with the same class of drugs? When do you give patients treatment holidays?