Panelists discuss the common toxicities associated with trifluridine-tipiracil plus bevacizumab in clinical practice, including their typical severity, and share their strategies for managing dose reductions and interruptions due to cytopenias when treating patients with this regimen.
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Let’s further discuss these agents’ safety profiles and management strategies.… Dr Fakih, could you please discuss common toxicities that clinicians may see with trifluridine-tipiracil plus bevacizumab in their day-to-day practice?
What is the usual severity?
What is your treatment strategy in terms of dose reduction and/or interruptions due to cytopenias with trifluridine-tipiracil plus bevacizumab?