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Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss data for lorlatinib in ROS1-positive NSCLC after crizotinib and chemotherapy.

Lorlatinib in ROS1+ Advanced NSCLC after Crizotinib and Chemotherapy

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The OncLive Precision Medicine in Oncology® condition center page is a comprehensive resource for clinical news and expert insights on precision-focused approaches in patients with cancer, with gene-targeted tyrosine kinase inhibitors and antibody-drug conjugates, checkpoint inhibitors, tumor-infiltrating lymphocyte therapy, and other tailored treatments. This page features news articles, interviews in written and video format, and podcasts that focus on updates and ongoing research with personalized therapies across solid and hematologic tumors.

Updates in Targeted Therapies for ALK+ and ROS1+ NSCLC from ESMO 2024

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Lorlatinib in ROS1+ Advanced NSCLC After Crizotinib and Chemotherapy

Testing for ALK Fusions and ROS1 Rearrangements in NSCLC

Data for NVL-655 in Advanced ALK+ NSCLC and Solid Tumors from the ALKOVE-1 Trial

Findings for Zidesamtinib in Advanced ROS1+ NSCLC and Other Solid Tumors

Preclinical CNS Data for Zidesamtinib and Other ROS1 Inhibitors

Progression Patterns and Subsequent Therapies after Lorlatinib in ALK+ NSCLC

The TRUST-II Study of Taletrectinib in ROS1+ Advanced NSCLC

Future Research Directions in ALK+ and ROS1+ NSCLC