Lower-Risk Myelodysplastic Syndromes (LR-MDS): Highlights from EHA 2024 - Episode 8

Exploring Biomarker Analysis, Real-World Data, and Quality of Life in LR-MDS: Insights from EHA 2024

July 23, 2024

Guillermo Garcia-Manero, MD, Rami Komrokji, MD, Esther Natalie Oliva, MD , Amer Zeidan, MBBS, MHS, Thomas Cluzeau, MD, PhD

Experts in lower-risk myelodysplastic syndromes analyze and interpret the comparative biomarker data on ring sideroblasts in LR-MDS patients from the COMMANDS study.

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EP. 1: Navigating Myelodysplastic Syndromes: Updates to WHO & ICC Guidelines, IPSS-M, and Risk Stratification

EP. 2: Dr Oliva on Addressing Challenges in Treating Lower-Risk MDS 

EP. 3: Frontline Therapy for Lower-Risk MDS: Global Perspectives and Treatment Selection Strategies

EP. 4: Review of the COMMANDS Trial

EP. 5: Perceptions of the EHA 2024 Full Analysis of the COMMANDs Trial

EP. 6: Clinical Implications of COMMANDS Trial in Clinical Practice

EP. 7: Treatment Decision-Making Based on the COMMANDS Trials

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EP. 8: Exploring Biomarker Analysis, Real-World Data, and Quality of Life in LR-MDS: Insights from EHA 2024

EP. 9: Dr.'s Cluzeau and Komrokji on Utilization Patterns of luspatercept in LR-MDS EHA 2024 Data

EP. 10: Safety Profile of Available Frontline Treatments LR-MDS

EP. 11: 1L treatment of lower-risk MDS beyond luspatercept

EP. 12: Sequencing Second-Line Treatments for LR-MDS

EP. 13: Perspectives of IMerge Study

EP. 14: Real-World Evidence and Emerging Therapies in Lower-Risk MDS: Insights from EHA 2024

EP. 15: EHA 2024 Future Directions in Lower-Risk MDS Treatment: Emerging Data, Approvals, and Guideline Updates

EP. 16: Final Thoughts on EHA 2024 Data for Lower-Risk MDS

What insights can you share on the comparative biomarker analysis on RS in patients with LR-MDS from the COMMANDS study?
Let’s continue our discussion by exploring real-world data and quality of life (QoL) findings in LR-MDS.
- For patients receiving luspatercept or epoetin alfa, how do you interpret the findings surrounding Hgb levels and improving QoL in transfusion-dependent patients with LR-MDS?