Dr. Wolchok on Remaining Questions Regarding Immunotherapies in Melanoma

Jedd D. Wolchok, MD, PhD, medical oncologist, Memorial Sloan Kettering Cancer Center, discusses remaining questions regarding immunotherapies for the treatment of melanoma.

Despite success, there are several questions that remain. One crucial area, Wolchok says, is the need identify biomarkers to enrich patient populations.

Research is also focusing on how to form rational, potent, and safe combinations of immunotherapies. Wolchok says research is also being conducted looking at combining immunotherapies and targeted therapies. This area is particularly important, as some targeted pathway inhibitors could have a positive or negative effect on immune cells, in addition to having activity against cancer cells.