The immuno-oncology condition center is a comprehensive resource for clinical news and expert insights on immuno-oncology. Read more at OncLive.
December 5th 2025
Adjuvant pembrolizumab delivers sustained clinical benefits across ccRCC subgroups with no new long-term safety signals.
December 4th 2025
PLN-101095 in combination with pembrolizumab led to responses in patients with ICI-refractory advanced solid tumors.
December 2nd 2025
The prescribing information for cosibelimab in advanced cutaneous squamous cell carcinoma was updated to include long-term data from the CK-301-101 trial.
In case you missed any, read a recap of every episode of OncLive On Air that aired in November 2025.
Here is your cheat sheet to all therapeutic options that were cleared by the FDA in November 2025 spanning tumor types.
December 1st 2025
Pembrolizumab obtained approval from the European Commission for subcutaneous administration for all adult indications.
November 29th 2025
The FDA approved a new option in resectable gastric cancer, and a new agent is under priority review in mantle cell lymphoma.
November 26th 2025
Vicky Makker, MD, discusses the DESTINY-Endometrial01 trial of T-DXd plus rilvegostomig or pembrolizumab in HER2+ pMMR endometrial cancer.
November 25th 2025
The FDA approved durvalumab plus FLOT for the perioperative treatment of resectable gastric and gastroesophageal junction cancers.
Subcutaneous toripalimab generated non-inferior efficacy and safety outcomes vs the IV formulation in recurrent/metastatic non squamous NSCLC.
November 24th 2025
Sacituzumab tirumotecan plus pembrolizumab improved PFS as first-line treatment in PD-L1–positive advanced NSCLC.
November 22nd 2025
The FDA approved 5 therapeutic options spanning lung cancer, urothelial cancer, NF1-associated PNs, and AL amyloidosis.
November 21st 2025
The FDA has approved neoadjuvant/adjuvant enfortumab vedotin plus pembrolizumab for cisplatin-ineligible muscle-invasive bladder cancer.
November 19th 2025
Cemiplimab wins EU approval after C-POST shows DFS gains for high-risk CSCC, marking the first effective adjuvant immunotherapy option.
November 15th 2025
The FDA has approved ziftomenib for NPM1-positive acute myeloid leukemia, has accepted a NDA for 177Lu-edotreotide for GEP-NETs, and more.
November 11th 2025
Researchers at The University of Texas MD Anderson Cancer Center shared insights about how the immune system can be trained to improve patient outcomes.
November 8th 2025
The FDA clears subcutaneous daratumumab in smoldering myeloma, adds REMS guidelines for pexidartinib in TGCT, and more.
November 5th 2025
The FDA has granted orphan drug designation to M2T-CD33 for the treatment of patients with acute myeloid leukemia.
October 31st 2025
Seven provinces have agreed to reimburse cemiplimab for the treatment of patients with advanced non–small cell lung cancer and basal cell carcinoma.
Here is your guide to all therapeutic options that were approved by the FDA in October 2025 spanning tumor types.