Rana R. McKay, MD, medical oncologist, assistant professor, Moores Cancer Center at the University of California, San Diego, discusses immunotherapy trials in renal cell carcinoma (RCC).

Data presented at the 2017 ESMO Congress showed that the combination of nivolumab (Opdivo) plus ipilimumab (Yervoy) improved survival and response rates for patients with intermediate- and poor-risk disease, says McKay.

Currently, there are phase III trials exploring combinations of VEGF and immunotherapy in RCC, such as the combination of cabozantinib (Cabometyx) plus nivolumab with or without ipilimumab, and the combination of axitinib (Inlyta) and pembrolizumab (Keytruda).

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The OncLive Genitourinary Cancer condition center page is a comprehensive resource for clinical news and expert insights across genitourinary (GU) malignancies, including renal cell carcinoma, urothelial carcinoma, and prostate cancer. This section features news articles, interviews in written and video format, and podcasts that focus on the evolving treatment paradigm of GU cancers and emerging research. 

Rana R. McKay, MD, medical oncologist, assistant professor, Moores Cancer Center at the University of California, San Diego, discusses immunotherapy trials in renal cell carcinoma.

Dr. McKay Discusses Immunotherapy Trials in RCC