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Biomarker Testing Best Practices in HR+/HER2- mBC

Please discuss the role of biomarker testing in HR+/HER2- breast cancer.

What are the most clinically relevant genomic tests or biomarker assays used in HR+/HER2- breast cancer?

How do the results of these tests influence prognosis and treatment decision-making?

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Video Series

Targeting the PI3K/AKT/PTEN Pathway in HR+/HER2- Locally Advanced and Metastatic Breast Cancer

Adam M. Brufsky, MD, PhD, and Erika P. Hamilton, MD, delve into the most clinically significant genomic tests and biomarker assays employed in HR+/HER2- breast cancer, focusing on BRCA mutations, PI3 alterations, AKT alterations, and PTEN alterations, which play crucial roles in determining prognosis and guiding treatment decisions. 