First AD

Second AD

Biological Mechanisms of GIST Resistance and Tumor Heterogeneity

Video content above is prompted by the following:

Let’s start with the fundamentals of resistance in GIST. Could you explain the biological mechanisms of resistance in GIST? Could you differentiate between primary and secondary resistance in GIST and explain how each impacts your treatment approach?

How does tumor heterogeneity evolve throughout treatment course, and what implications does this have for long-term management?

Video Series

Insights

Insights is an expert interview video series of leading oncologists that provides in-depth reports and feature segments profiling leaders in a range of oncology disciplines, including breast cancer, lung cancer, gastrointestinal cancers, genitourinary cancers, gynecologic cancers, and hematologic malignancies. Most episodes feature 2 clinicians discussing the latest oncology advances in clinical practice. 

My Treatment Approach Beyond the First-Line: Expert Insights on Evidence-Driven TKI Selection and Sequencing in Advanced GIST

OncLive Insights

Experts discuss the biological mechanisms of resistance in gastrointestinal stromal tumors (GIST), differentiating between primary and secondary resistance, and explore how tumor heterogeneity evolves throughout treatment, with implications for long-term management and treatment strategies.