Updates in Targeted Therapies for ALK+ and ROS1+ NSCLC from ESMO 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss updates in ALK-positive and ROS1-positive non–small cell lung cancer.

EP. 1: Testing for ALK Fusions and ROS1 Rearrangements in NSCLC

October 25th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss testing for ALK-positive and ROS1-positive non–small cell lung cancer.

EP. 2: Data for NVL-655 in Advanced ALK+ NSCLC and Solid Tumors from the ALKOVE-1 Trial

October 25th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss data for NVL-655 in ALK-positive NSCLC and other ALK-positive solid tumors.

EP. 3: Findings for Zidesamtinib in Advanced ROS1+ NSCLC and Other Solid Tumors

October 28th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss data for zidesamtinib in ROS1-positive non–small cell lung cancer.

EP. 4: Preclinical CNS Data for Zidesamtinib and Other ROS1 Inhibitors

October 28th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss preclinical CNS data for the ROS1 inhibitor zidesamtinib.

EP. 5: Progression Patterns and Subsequent Therapies after Lorlatinib in ALK+ NSCLC

October 28th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss progression patterns and therapies after lorlatinib in ALK-positive NSCLC.

EP. 6: The TRUST-II Study of Taletrectinib in ROS1+ Advanced NSCLC

October 29th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss data for taletrectinib in ROS1-positive advanced non–small cell lung cancer.

EP. 7: Lorlatinib in ROS1+ Advanced NSCLC After Crizotinib and Chemotherapy

October 29th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss data for lorlatinib in ROS1-positive NSCLC after crizotinib and chemotherapy.

EP. 8: Future Research Directions in ALK+ and ROS1+ NSCLC

October 29th 2024

Gregory J. Riely, MD, PhD, and Benjamin Besse, MD, discuss unmet needs and future research directions in ALK-positive and ROS1-positive NSCLC.