Navigating First- and Second-Line Therapies in Extensive-Stage Small Cell Lung Cancer

Panelists discuss evolving first- and second-line treatment strategies for extensive-stage small cell lung cancer, emphasizing evidence-based integration of immunotherapy, personalized maintenance approaches, toxicity management, and the promise of emerging targeted and immune-based therapies to improve survival and quality of life.

EP. 1: Introduction and Case 1: Diagnostic Workup of Patients with SCLC

October 29th 2025

Panelists discuss the diagnostic evaluation and staging process for extensive-stage small cell lung cancer, emphasizing comprehensive imaging and laboratory workup to guide initial treatment planning.

EP. 2: Treatment of SCLC Based on Patient Characteristics

October 29th 2025

Panelists discuss how patient and disease factors, such as performance status, comorbidities, and extent of metastases, influence first-line treatment selection in small cell lung cancer.

EP. 3: Safety and Efficacy of SCLC Treatments Based on Trial Data

October 30th 2025

Panelists review key clinical trial data demonstrating the efficacy and safety of chemo-immunotherapy regimens in extensive-stage small cell lung cancer.

EP. 4: Treatment Selection and Monitoring/Maintenance in Patients With SCLC

October 30th 2025

Panelists discuss practical considerations in selecting first-line regimens and managing maintenance therapy in patients responding to initial treatment.

EP. 5: IMforte Trial: Applying the Results in Practice

October 30th 2025

Panelists discuss the clinical relevance of emerging trial data evaluating combination maintenance strategies and their potential role in practice.

EP. 6: Case 2: Treatment of Recurring SCLC With Brain Metastasis and AE Management

October 30th 2025

Panelists discuss therapeutic strategies for recurrent small cell lung cancer with central nervous system involvement, emphasizing adverse event (AE) management and patient support.

EP. 7: Adherence to Treatment, Shared Decision-Making, and Patient Communication

October 30th 2025

Panelists discuss the importance of shared decision-making, patient communication, and adherence strategies in small cell lung cancer treatment.

EP. 8: Case 3: Second-Line Treatment for SCLC

October 30th 2025

Panelists discuss treatment decision-making in second-line small cell lung cancer, balancing efficacy, toxicity, and patient-specific factors.

EP. 9: Experience With Lurbinectedin in SCLC

October 30th 2025

Panelists discuss real-world experiences with novel agents for relapsed small cell lung cancer, focusing on efficacy, safety, and patient selection.

EP. 10: Emerging Therapies for SCLC

October 30th 2025

Panelists discuss novel and investigational therapies under study for small cell lung cancer, including immunotherapy combinations and targeted approaches.