Introduction and Case 1: Diagnostic Workup of Patients with SCLC

The discussion begins with a case highlighting a newly diagnosed patient with extensive-stage small cell lung cancer. Panelists emphasize that early, accurate diagnosis and staging are essential for effective treatment selection. The diagnostic process typically includes chest CT, PET/CT, and brain MRI to assess systemic spread, along with laboratory evaluations such as LDH and sodium levels to determine disease burden and organ function.

Panelists stress that staging helps identify patients who may benefit from more aggressive or targeted therapy and distinguishes extensive from limited-stage disease, which carries distinct treatment pathways. They note that small cell lung cancer often presents with widespread involvement at diagnosis, making early systemic therapy critical.

Ultimately, the conversation underscores that multidisciplinary coordination—radiology, pathology, and oncology—is key to ensuring accurate diagnosis and timely initiation of therapy. Proper assessment lays the foundation for individualized treatment plans and improved outcomes.