HER2+ Breast Cancer | Specialty

1-Year of Adjuvant Trastuzumab Remains Standard in HER2+ Breast Cancer

December 7th 2017

The phase III SOLD trial failed to demonstrate that DFS with 9 weeks of adjuvant trastuzumab was noninferior to the standard 12 months when the 2 regimens were combined with chemotherapy in women with early stage HER2-positive breast cancer.

Trastuzumab Disappoints in HER2-low Patient Cohort

December 6th 2017

A trial to determine the value of trastuzumab plus standard adjuvant chemotherapy in patients with low levels of HER2 protein has shown no significant efficacy, confounding investigators who launched the trial based on opposing results from 2 earlier studies.

Expert Emphasizes Importance of Neoadjuvant Therapy in HER2+ Breast Cancer

November 29th 2017

Patrick Borgen, MD, discusses the importance of neoadjuvant therapy in the treatment of patients with HER2-positive breast cancer.

Dr. Pusztai on Challenges With Neoadjuvant HER2 Therapy

November 28th 2017

Lajos Pusztai, MD, professor of medicine, chief of Breast Medical Oncology, Yale Cancer Center and Yale School of Medicine, discusses the challenges facing neoadjuvant treatment of patients with HER2-positive breast cancer

Adjuvant Treatment Evolving for HER2+ Breast Cancer

November 27th 2017

Sara M. Tolaney, MD, discusses the state of adjuvant treatment for patients with HER2-positive breast cancer.

Expert Highlights Expanding Options for HER2+ Breast Cancer

November 27th 2017

Lajos Pusztai, MD, discusses neoadjuvant and adjuvant treatment decisions for patients with HER2-positive breast cancer, as well as the potential of immunotherapy in the metastatic setting.

Dr. Borgen on Advancements With HER2+ Breast Cancer

November 17th 2017

Patrick Borgen, MD, chair, Department of Surgery, director, Breast Center, Maimonides Medical Center, discusses advancements in the treatment landscape of HER2-positive breast cancer.

Dr. Brufsky Discusses Pertuzumab in HER2+ Breast Cancer

November 14th 2017

Adam M. Brufsky, MD, PhD, professor of medicine, associate chief of Hematology/Oncology, co-director of the Comprehensive Breast Care Center, associate director of Clinical Investigation, University of Pittsburgh, discusses pertuzumab (Perjeta) in HER2-positive breast cancer.

Dr. Tolaney on the ATEMPT Trial for HER2+ Breast Cancer

November 9th 2017

Sara M. Tolaney, MD, MPH, instructor of medicine, Harvard Medical School, attending physician of medical oncology, Dana-Farber Cancer Institute, discusses the ATEMPT trial for patients with HER2-positive breast cancer.

Neoadjuvant Treatment Evolving in HER2-Positive Breast Cancer

October 31st 2017

Elizabeth A. Mittendorf, MD, PhD, discusses the evolving neoadjuvant treatment landscape and other developments in the field of HER2-postive breast cancer.

Neratinib Offers Hope in Treatment of CNS Metastases in HER2+ Breast Cancer

October 25th 2017

Rachel A. Freedman, MD, discusses treating patients with HER2-positive breast cancer who develop CNS metastases, and the promise that neratinib holds in this patient population.

Hamilton Highlights Progress in HER2-Positive Breast Cancer

October 25th 2017

Erika P. Hamilton, MD, discusses the current treatment landscape for patients with HER2-positive breast cancer.

Dr. Hamilton Discusses Tucatinib in HER2+ Breast Cancer

October 24th 2017

Erika P. Hamilton, MD, director of the Breast and Gynecologic Research Program at Sarah Cannon Research Institute, discusses tucatinib in the treatment of patients with HER2-positive breast cancer.

Dr. Gradishar Discusses Dual HER2-Targeting in Breast Cancer

October 18th 2017

William J. Gradishar, MD, interim chief of Hematology and Oncology in the Department of Medicine, Betsy Bramsen Professorship of Breast Oncology, professor of medicine (hematology and oncology), Feinberg School of Medicine, Northwestern University, discusses dual HER2-targeting in breast cancer.

Dr. Hamilton on Extended Adjuvant Therapy for HER2+ Breast Cancer

October 16th 2017

Erika P. Hamilton, MD, director of the Breast and Gynecologic Research Program at Sarah Cannon Research Institute, discusses the role of extended adjuvant therapy for patients with HER2-positive breast cancer.

Dr. Gradishar on the Role of Neratinib in the Treatment of HER2+ Breast Cancer

October 13th 2017

William J. Gradishar, MD, interim chief of Hematology and Oncology in the Department of Medicine, Betsy Bramsen Professorship of Breast Oncology, professor of Medicine, Hematology and Oncology, Northwestern University Feinberg School of Medicine, discusses the role of neratinib (Nerlynx) in the treatment of patients with HER2-positive breast cancer.

Dr. Muss on Determining Treatments for HER2+ Breast Cancer

October 10th 2017

Hyman B. Muss, MD, professor of medicine, University of North Carolina-Chapel Hill School of Medicine, Breast Cancer Geriatric Oncology Program, director, geriatric oncology, UNC Lineberger Comprehensive Cancer Center, 2017 Giant of Cancer Care in Supportive/Palliative/Geriatric Care, discusses determining treatments for patients with HER2-positive breast cancer.

Dr. Hamilton on How Neratinib Targets HER2+ Breast Cancer

October 8th 2017

Erika P. Hamilton, MD, director of the Breast and Gynecologic Research Program at Sarah Cannon Research Institute, discusses how neratinib (Nerlynx) targets HER2-positive breast cancer.

The Path Forward in Breast Cancer Research

October 5th 2017

AR-Targeted Therapy and Immunotherapy for TNBC

October 5th 2017