HER2+ Breast Cancer | Specialty

Widespread Mutation Testing for NSCLC

August 29th 2017

Genetic Testing for NSCLC

August 29th 2017

Dr. Tolaney Discusses Neratinib in HER2+ Breast Cancer

August 25th 2017

Sara M. Tolaney, MD, MPH, instructor of medicine, Harvard Medical School, attending physician of medical oncology, Dana-Farber Cancer Institute, discusses neratinib (Nerlynx) in HER2-positive breast cancer.

Frontline Ribociclib Approved in Europe for HR+/HER2- Breast Cancer

August 24th 2017

The European Commission has approved the CDK 4/6 inhibitor ribociclib for use in combination with an aromatase inhibitor for the frontline treatment of postmenopausal women with hormone-receptor (HR)–positive, HER2-negative locally advanced or metastatic breast cancer.

Gradishar Sheds Light on Treatment Trends in Breast Cancer

August 22nd 2017

William J. Gradishar, MD, discusses the latest developments in the HER2-positive setting, as well as biomarker development and the potential for immunotherapy in breast cancer.

Dr. Gradishar on Selecting Agents for HER2+ Breast Cancer

August 18th 2017

William J. Gradishar, MD, interim chief of Hematology and Oncology in the Department of Medicine, Betsy Bramsen Professorship of Breast Oncology, professor of Medicine (Hematology and Oncology), Northwestern University Feinberg School of Medicine, discusses selecting agents for the treatment of patients with HER2-positive breast cancer.

Lead Researcher Discusses Latest Pertuzumab Data in HER2+ Breast Cancer

August 12th 2017

Gunter von Minckwitz, MD, PhD, discusses the APHINITY results and their implication for the use of pertuzumab in patients with HER2-positive breast cancer.

Neoadjuvant T-DM1 Improves pCR in HER2+/HR+ Early Breast Cancer

August 11th 2017

Twelve weeks of neoadjuvant T-DM1 with or without endocrine therapy induced superior pathologic complete response compared with trastuzumab (Herceptin) plus endocrine therapy in patients with HER2-positive/HR-positive early breast cancer.

Dr. Pegram on Pertuzumab Combination for HER2-Positive Breast Cancer

August 11th 2017

Mark D. Pegram, MD, director of the Breast Cancer Oncology Program at Stanford Medicine, discusses pertuzumab (Perjeta) plus trastuzumab (Herceptin) and chemotherapy for patients with HER2-positive breast cancer.

Pegram Discusses Latest Developments in HER2+ Breast Cancer

August 9th 2017

Mark Pegram, MD, discusses emerging treatments in HER2-positive breast cancer and his vision for the future of the field.

Sequenced Treatment Making Inroads in HER2-Positive Early Breast Cancer

August 2nd 2017

The introduction of targeted therapies has transformed HER2-positive breast cancer from an aggressive disease with poor outcomes to a highly manageable disease with potential for long-term survival.

Dr. Tolaney on Neoadjuvant HER2-Directed Therapy

August 2nd 2017

Sara M. Tolaney, MD, MPH, instructor of medicine, Harvard Medical School, attending physician of medical oncology, Dana-Farber Cancer Institute, discusses neoadjuvant HER2-directed therapy.

Trastuzumab Combos, Novel Agents Key to Advancing HER2+ Breast Cancer Care

July 28th 2017

Experts are trying to determine whether combination regimens with additional HER2-directed therapies or alternative therapies could improve responses in HER2-positive breast cancer without added toxicities.

FDA Approves Neratinib for HER2+ Breast Cancer

July 18th 2017

The FDA has approved neratinib (Nerlynx) for the extended adjuvant treatment of patients with early stage, HER2-positive breast cancer following postoperative trastuzumab.

Dr. Pegram on Pertuzumab Plus Trastuzumab and Chemotherapy in Breast Cancer

July 15th 2017

Mark D. Pegram, MD, associate director, clinical research, director, Breast Cancer Program, Stanford Cancer Institute, discusses the current treatment landscape for patients with HER2-positive breast cancer.

ODAC Votes to Recommend Approval for Trastuzumab Biosimilar MYL-1401O

July 14th 2017

The FDA’s Oncologic Drugs Advisory Committee voted 16-0 to recommend approval to MYL-1401O, the trastuzumab (Herceptin) biosimilar manufactured by Mylan Pharmaceuticals.

Dr. Burstein on the Results of the APT Trial for HER2+ Breast Cancer

July 13th 2017

Harold J. Burstein, MD, PhD, senior physician, associate professor of medicine, Harvard Medical School, Dana-Farber Cancer Institute, discusses the results of the APT trial investigating adjuvant paclitaxel and trastuzumab (Herceptin) for node-negative HER2-positive breast cancer.

Lapatinib/Trastuzumab/AI Triplet Nearly Doubles PFS in HER2+/HR+ Metastatic Breast Cancer

July 7th 2017

The triplet combination of HER2-targeted therapy and an aromatase inhibitor improved progression-free survival by more than 5 months compared with the combination of trastuzumab (Herceptin) and an aromatase inhibitor in patients with HER2+/HR+ breast cancer.

Dr. Yardley on the Results of the APT and APHINITY Trials for HER2+ Breast Cancer

July 7th 2017

Denise Yardley, MD, senior investigator at the Sarah Cannon Research Institute, discusses the results of the APT and APHINITY trials for patients with HER2-positive breast cancer.

Dr. Freedman Discusses Dual HER2-Targeted Therapy in Breast Cancer

June 29th 2017

Rachel A. Freedman, MD, MPH, associate clinical director, Breast Oncology Center, Susan F. Smith Center for Women's Cancers, Dana-Farber Cancer Institute, senior physician, assistant professor of medicine, Harvard Medical School, discusses dual HER2-targeted therapies in breast cancer.