Precision Medicine in Oncology® | Specialty

The OncLive Precision Medicine in Oncology® condition center page is a comprehensive resource for clinical news and expert insights on precision-focused approaches in patients with cancer, with gene-targeted tyrosine kinase inhibitors and antibody-drug conjugates, checkpoint inhibitors, tumor-infiltrating lymphocyte therapy, and other tailored treatments. This page features news articles, interviews in written and video format, and podcasts that focus on updates and ongoing research with personalized therapies across solid and hematologic tumors.

Dr. Vogelzang Discusses Cabozantinib Trial Design

June 9th 2011

Dr. Vogelzang from the Comprehensive Cancer Centers of Nevada Discusses Cabozantinib Trial Design

Dr. Cella on Patient Assessment Reference Scores

June 5th 2011

Dr. Cella from Northwestern University Feinberg School of Medicine on Patient Assessment Reference Scores

Molecular Profiling Boosts Targeted Therapies in Phase I Trial

June 4th 2011

Matching patients with targeted therapies based on molecular profile results in superior clinical outcomes

Attacking the Frontiers of Breast Cancer: A Conversation With Joyce A. O'Shaughnessy, MD

June 3rd 2011

As a child Joyce Ann O'Shaughnessy enjoyed science and her home chemistry set. Still, she didn't give much thought to pursuing the subject beyond the confines of her school - until she faced a tragedy.

Experimental Melanoma Vaccine May Shrink Late-Stage Tumors

June 2nd 2011

An experimental melanoma vaccine gp100 peptide vaccine in combination with IL2 may shrink tumors and prevent the progression of late-stage melanoma

A Tale of 2 Complexes: The mTOR Signaling Pathway in Cancer Development

June 2nd 2011

The mammalian target of rapamycin (mTOR) is a master switch, central regulator, or key integrator of cell growth and proliferation

Fine-Tuning Cancer Care: NCCN Changes 11 Guidelines

June 1st 2011

Highlights on updates to the clinical practice guidelines from the annual National Comprehensive Cancer Network (NCCN) conference

Climbing to New Heights: James Berenson, MD, and the Institute for Myeloma and Bone Cancer Research

May 27th 2011

Oncologist James Berenson, MD, likes all of his patients, especially the ones with whom he skis.

Donna Berry on the Future of Oncology Nursing

May 26th 2011

Donna Berry from the Phyllis F. Cantor Center at the Dana-Farber Cancer Institute on the Future of Oncology Nursing

Beyond Broccoli: Cancer Focus Is on Food at Molecular Levels

May 25th 2011

The past decade has brought a significant increase in attention to the role that food and nutrients might play in fighting cancer.

Oncology Links From Across the Web for Brain Cancer

May 19th 2011

Links to resource from across the web for brain cancer; includes news briefs, patient education, research and clinical trials

Cabozantinib (XL184) Demonstrates Antitumor Activity and Reduces or Eliminates Bone Metastases in Multiple Cancers

May 18th 2011

Cabozantinib (XL184), an investigational oral tyrosine kinase inhibitor, demonstrated antitumor activity in multiple types of advanced solid tumors.

Dr. Pecora on the Pathway Inhibitor Cabozantinib

May 18th 2011

Dr. Pecora on the Pathway Inhibitor Cabozantinib (XL184)

Jane Armer on Findings From Her Lymphedema Research

May 17th 2011

Jane Armer the director of ALFP on Findings From Her Lymphedema Research

Genomic Test Helps Define Primary Tumor: An Interview With William David Henner, MD, PhD

May 16th 2011

As cancer-fighting therapies become more targeted, clinicians are looking increasingly toward emerging technologies to help confirm the primary site of a patient's disease.

5 Hedgehog Pathway Questions for Michael T. Lewis

May 13th 2011

Michael T. Lewis, PhD, runs a research lab at the Baylor College of Medicine focused on understanding the role of hedgehog signaling in mammary gland development and breast cancer

Ferreting Out the Hedgehog Pathway Emerges as Ripe Target for Cancer Drug Development

May 13th 2011

The Hedgehog gene is an intracellular signaling ligand that initiates the Hh pathway, which is important in the regulation of embryo development from flies to humans

Roswell Park Cancer Institute: A History of Initiative and Innovation

May 12th 2011

Founded in 1898 by Dr Roswell Park, Roswell Park Cancer Institute (RPCI) is the oldest dedicated comprehensive cancer center in the country

Medicine Is in His DNA: Giant in Breast Gene Research Draws on Childhood Values

May 11th 2011

Plenty of children are afraid to go to the doctor. Dennis Slamon used to look forward to it.

Dr. Edith Perez Discusses Her Ongoing Research

April 27th 2011