Precision Medicine in Oncology® | Specialty

Selecting Treatment for First- Line Non-Squamous NSCLC

February 13th 2013

Selecting a Laboratory for Molecular Testing in NSCLC

February 13th 2013

Rebiopsying and Molecular Testing in NSCLC

February 13th 2013

Molecular Testing and Actionable Targets in NSCLC

February 13th 2013

Best Practices in NSCLC Molecular Testing, Part II

February 13th 2013

Concurrent Versus Sequential Testing in NSCLC

February 13th 2013

Best Practices in NSCLC Molecular Testing, Part I

February 13th 2013

Introduction: Advances and Issues in NSCLC

February 13th 2013

Squamous Cell Carcinoma Treatment Options

February 13th 2013

A Journey of a Lifetime: Noted Breast Cancer Researcher in Far-Flung Pursuit of a "Cure"

February 12th 2013

Leyland-Jones, MB BS, PhD, a renowned oncologist and translational scientist, has helped develop several mainstay oncologic treatments and the targeted breast cancer therapy trastuzumab.

Targeting Tumors Early: Trials Push Novel Agents to Forefront

February 11th 2013

New discoveries about tumor biology suggest to many researchers that targeted therapies, when used in appropriate early-stage patients, might significantly boost cure rates and extend lives.

Dr. Abou-Alfa on MET Inhibition in Liver Cancer

February 11th 2013

Ghassan K. Abou-Alfa, MD, from Memorial Sloan-Kettering Cancer Center, discusses the promising results and future investigation of MET inhibition in hepatocellular carcinoma using cabozantinib and tivantinib.

BATTLE-2: Next-Generation of Biomarker-Driven Trials

February 8th 2013

While the number of known mutations and matching targeted agents is relatively limited at present, clinical trials are being designed to identify effective therapies for specific mutations more efficiently.

Innovative BATTLE Trials Pair Agents, Biomarkers in NSCLC

February 7th 2013

As therapy based on cell-signaling pathways has become a priority in cancer research, so has the concept of designing clinical trials that can better target patient populations more likely to benefit from a particular regimen.

HER2 Mutations Identified as Treatment Targets in Patients With HER2-Negative Breast Cancer

February 5th 2013

Patients with breast cancer who do not exhibit amplifications of the HER2 gene may still have mutations of HER2 that drive the progression of their cancer, suggesting that these mutations could serve as therapeutic targets.

Potential Treatment Combinations for Melanoma Identified Through Novel Screening Approach

February 4th 2013

A new drug screening method revealed that cholesterol-reducing statin drugs used in combination with cyclin-dependent kinase inhibitors might serve as an effective treatment approach for certain types of melanoma.

ADCs Are Poised to "Blossom" as a New Category of Therapy: An Interview With John M. Lambert, PhD

February 1st 2013

Antibody-drug conjugates are a robust area of oncology exploration, with an estimated 25 ADCs under study in clinical trials, up from six less than a decade ago.

Proto-oncogene Responsible for Ovarian Cancer Metastasis Identified

January 29th 2013

Activation of a signaling pathway involving the proto-oncogene Src is responsible for disease progression and metastasis in cancer and beta blocker drugs could be used to reduce mortality in these patients.

Dr. John Byrd on Bruton's Tyrosine Kinase in CLL

January 29th 2013

John C. Byrd, MD, director of the division of hematology at The Ohio State University Comprehensive Cancer Center, discusses the role of Bruton's Tyrosine Kinase (BTK) in chronic lymphocytic leukemia.

Dr. Grady Discusses Molecular Subtypes in Colorectal Cancer

January 25th 2013

William M. Grady, MD, from the Fred Hutchinson Cancer Research Center, discusses results from a study that examined the association of intrinsic subtypes of colorectal cancer with prognosis, chemotherapy response, and other factors.