Virginia G. Kaklamani, MD, DSc

Articles

How Does Response to Neoadjuvant Therapy Affect Prognosis and Inform Adjuvant Selection?

July 6th 2023

Dr Tripathy provides clinical insight on how he assesses HER2+ eBC patient response to neoadjuvant therapy, discusses the typical prognosis for those who do or do not have residual disease, and touches on how he might approach adjuvant treatment selection for each.

Factors Informing the Selection and Use of OFS in Breast Cancer

July 5th 2023

Expert perspectives on the appropriate selection and use of OFS in premenopausal patients with breast cancer.

Data From the SOFT and TEXT Trials: Combination Therapy With OFS in Breast Cancer

July 5th 2023

Matteo Lambertini, MD, PhD, and Virginia Kaklamani, MD, DSc, reflect on the SOFT and TEXT clinical trials to elucidate combination treatment strategies with ovarian function suppression (OFS).

Neoadjuvant Systemic Therapy for HER2+ eBC: Clinical Considerations and Evolving Modalities

June 29th 2023

Panelists expand upon the most important clinical factors that inform selection amongst available systemic therapy regimens in the neoadjuvant setting of HER2+ eBC, comment on the potential for treatment de-escalation in lower-risk patients, and discuss exciting treatments on the horizon.

HER2+ Early Breast Cancer: Treatment Optimization and Review of Standard-of-Care Neoadjuvant Regimens

June 29th 2023

Heather McArthur, MD, and Debu Tripathy, MD, lead a discussion on risk stratification and optimizing treatment for HER2+ early breast cancer (eBC), followed by a review of standard-of-care systemic therapy regimens in the preoperative/neoadjuvant setting.

Fertility Preservation in Breast Cancer: Use of GnRH Agonists

June 28th 2023

Comprehensive insight to available gonadotropin-releasing hormone (GnRH) agonists in breast cancer and the role they play when thinking about fertility preservation.

Overview of Fertility Preservation Strategies in Breast Cancer Care

June 28th 2023

Key opinion leaders on breast cancer management provide a broad overview of fertility preservation strategies available to patients.

Addressing Chemotherapy-Induced Menopause in Patients With Breast Cancer

June 21st 2023

Focused discussion on the incidence of chemotherapy-induced menopause in patients receiving treatment for their breast cancer.

Prevalence of Premenopausal Patients With Breast Cancer

June 21st 2023

Expert oncologists Matteo Lambertini, MD, PhD, and Virginia Kaklamani, MD, DSc, reflect on the subset of patients with breast cancer who are premenopausal and how that impacts their approach to disease management.

Overview of the HER2+ Metastatic Breast Cancer Treatment Armamentarium

June 5th 2023

A key opinion leader in breast cancer management shares insight on the treatment armamentarium for patients with HER2+ disease.

Evolution in the Field of HR+ Breast Cancer Management

March 16th 2023

Closing out their discussion on HR+ breast cancer management, expert panelists share their excitement for the evolving treatment paradigm.

Dr. Kaklamani on CDK4/6 Inhibition Prior to Elacestrant in ER+/HER2– Breast Cancer

March 10th 2023

Virginia Kaklamani, MD, discusses the utilization of elacestrant following treatment with CDK4/6 inhibitors in patients with estrogen receptor-positive, HER2-negative metastatic breast cancer.

Other Treatment Modalities for HR+ Metastatic Breast Cancer

March 9th 2023

Comprehensive discussion on novel treatment modalities in HR+ metastatic breast cancer and insight to when it is appropriate to select these agents.

HR+ Metastatic Breast Cancer: Optimal Selection of Endocrine Partners

March 9th 2023

Shared insight on the selection of endocrine partners while managing patients in the relapsed/refractory setting of HR+ metastatic breast cancer.

Advice for Community Physicians on Managing HER2+ Breast Cancer

March 7th 2023

Closing out their review on treatment strategies for HER2-expressing breast cancer, panelists share practical advice for the community setting.

Continuing CDK4/6 Inhibition at Progression of HR+ Metastatic Breast Cancer

March 2nd 2023

Key opinion leaders consider when it is appropriate to continue CDK4/6 inhibition at progression of disease in the setting of HR+ metastatic breast cancer.

Molecular Testing in Relapsed/Refractory HR+ Metastatic Breast Cancer

March 2nd 2023

A brief review of the role molecular profiling plays at a patient’s relapse with HR+ metastatic breast cancer.

Potential Role for T-DXd in Early-Stage HER2-Low Breast Cancer

February 28th 2023

Panelists share a brief discussion on early-stage HER2-low breast cancer and identify treatment options available in that setting.

Optimizing Real-World Management of HER2-Low Breast Cancer

February 28th 2023

Comprehensive insight on evolving management strategies for patients diagnosed with HER2-low breast cancer.

Factors in Selecting 1L Therapy for Patients With HR+ Metastatic Breast Cancer

February 23rd 2023

Expert perspectives on factors that aid in the selection of optimal first-line therapy for patients with HR+ metastatic breast cancer.