Jill Stein

Articles

Dacomitinib Bests Erlotinib in Advanced Non-Small Cell Lung Cancer

October 23rd 2012

Treatment with the investigational agent dacomitinib improved PFS when compared with erlotinib in patients with non–small cell lung cancer experiencing progression during chemotherapy.

Adjuvant Chemotherapy May Offer Survival Benefit in Older Patients With Colon Cancer

October 17th 2012

Patients 75 years of age or older with stage III colon cancer may expect a survival benefit from adjuvant chemotherapy that rivals that previously reported in younger patients.

Aprepitant Helps Prevent CINV in Men With Germ Cell Tumors

October 10th 2012

The addition of aprepitant to standard antiemetic prophylaxis significantly improved the complete response rate in patients with germ cell tumors undergoing 5-day cisplatin combination chemotherapy regimens.

No Survival Benefit With Add-On Sorafenib in Advanced Lung Cancer

October 9th 2012

The addition of sorafenib to first-line gemcitabine/cisplatin does not appear to lengthen survival in patients with advanced, nonsquamous, non–small cell lung cancer.

First-Line Dose-Dense Induction and High-Dose Chemotherapy/Autologous Stem Cell Transplant Benefits Patients With Rare Lymphomas

October 8th 2012

Dose-dense induction with high-dose chemotherapy/autologous stem-cell transplantation is reasonable for use as first-line treatment of transplantation-eligible patients with systemic peripheral T-cell lymphomas.

Everolimus Plus Tamoxifen Delivers Benefits in Hormone-Resistant mBC

October 4th 2012

Combining tamoxifen with everolimus increased the clinical benefit rate, time to progression, and overall survival versus tamoxifen alone in postmenopausal women with metastatic breast cancer.

Decitabine Outperforms Standard Treatments in Older Patients With Acute Myeloid Leukemia

September 27th 2012

Decitabine produced a higher response rate than standard therapies in older patients with newly diagnosed acute myeloid leukemia without major differences in safety.

Subcutaneous Trastuzumab May Offer Benefits Over Standard IV Infusion in Patients With Breast Cancer

September 26th 2012

A new formulation of trastuzumab that is administered subcutaneously appears to be as effective as the approved bodyweight-based intravenous regimen in women with HER2-positive breast cancer.

Biomarker Predicts Survival Benefit in Advanced Kidney Cancer Treated With TORC1 Inhibitor

September 26th 2012

Pretreatment serum lactate dehydrogenase is a prognostic factor in poor-risk patients with renal cell carcinoma and also a predictive factor for a survival benefit from treatment with temsirolimus.

Breast Cancer and Its Treatment May Not Cause Long-Term Fatigue

September 11th 2012

New data show that cancer-related fatigue is reported by only "a small minority" of women >6 months after completing adjuvant therapy for breast cancer.

Less Aggressive Surgery Linked to Improved Survival in Older Patients With Kidney Cancer

September 11th 2012

Partial nephrectomy is associated with better overall survival than radical nephrectomy in older patients with early-stage kidney cancer.

Vismodegib Effective Against Skin Cancer in Patients With Basal-Cell Nevus Syndrome

August 31st 2012

The oral hedgehog pathway inhibitor vismodegib is effective for both the prevention and treatment of basal-cell carcinoma in patients with the rare disorder known as basal-cell nevus syndrome.

Lenalidomide Maintenance After Stem-Cell Transplantation Benefits Patients With Multiple Myeloma

August 31st 2012

Lenalidomide used continuously after autologous hematopoietic stem cell transplantation significantly prolonged the time to disease progression and overall survival in patients with multiple myeloma.

Colonoscopy Linked With Lower Risk of Colorectal Cancer Mortality

August 24th 2012

Colonoscopy is effective for the prevention of colorectal cancer deaths, according to the results of a large, population-based, case-control study.

Radiation Oncologists Often Excluded From Breast Cancer Treatment Decisions

August 23rd 2012

A "substantial minority" of radiation oncologists report that surgeons fail to include them in the breast cancer treatment decision-making process before definitive surgery.

Naproxen Cuts Pegfilgrastim-Induced Bone Pain

August 20th 2012

The nonsteroidal anti-inflammatory drug naproxen significantly decreases the incidence, severity, and duration of pegfilgrastim-induced bone pain in patients diagnosed with a nonmyeloid cancer.

Black Men With Advanced Prostate Cancer May Benefit From Sipuleucel-T

July 18th 2012

Preliminary data suggest a promising role for sipuleucel-T as a treatment for African-American men with metastatic castration-resistant prostate cancer (mCRPC).

Healthy Lifestyle Improves Sexual Function Post-Prostatectomy

July 17th 2012

Patients with prostate cancer can expect better sexual function after a robotic-assisted radical prostatectomy (RARP) if they maintain a healthy lifestyle.

Ingenol Mebutate Gel Is Effective and Safe for Actinic Keratosis

July 12th 2012

Field-directed treatment with the investigational topical agent ingenol mebutate has been shown to be effective for actinic keratoses on the head and body.

Marital Status Impacts Survival in Prostate Cancer Patients

July 11th 2012

Marital status is an independent predictor of disease-related mortality and overall mortality in men with prostate cancer.

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