Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, is a consultant hematologist at King's College Hospital NHS Foundation Trust in London.

Articles

Addressing Further Unmet Needs in PNH

July 30th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, discuss unmet needs to address in the management of PNH.

Implications of APPULSE-PNH Data for Iptacopan in PNH

July 30th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, discuss implications of data from the APPULSE-PNH trial of iptacopan.

Factors for Selecting Iptacopan in C5 Inhibitor–Naive and –Exposed PNH

July 23rd 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, detail factors for selecting iptacopan in C5 inhibitor–naive and –exposed PNH.

Data for Iptacopan in PNH After Switching Anti-C5 Therapy: The APPULSE-PNH Trial

July 16th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, on data for iptacopan in PNH after switching anti-C5 therapy.

Implications of the FDA Approval of Iptacopan for PNH

July 9th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, on the implications of the FDA approval of Iptacopan for PNH.

Role of C5 Inhibitors in the Management of Paroxysmal Nocturnal Hemoglobinuria

July 2nd 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, on the current management of paroxysmal nocturnal hemoglobinuria.

APPULSE-PNH: Oral Iptacopan Monotherapy Demonstrates Clinically Meaningful Hemoglobin (Hb) Increases in Patients (Pts) With Paroxysmal Nocturnal Hemoglobinuria (Pnh) and Hb ≥10 G/Dl Oo Anti-C5 Therapy

June 26th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, presents results from the phase 3b APPULSE-PNH trial at the 2025 EHA Congress in Milan, Italy. The data demonstrate that, in patients with PNH and hemoglobin ≥10 g/dL who switched from anti-C5 therapy to iptacopan, iptacopan was superior in improving hemoglobin levels from baseline.

Reviewing Current Standards in Paroxysmal Nocturnal Hemoglobinuria

June 24th 2025

Austin Kulasekararaj, MBBS, MD, MRCP, FRCPath, and David Dingli, MD, PhD, on the current management of paroxysmal nocturnal hemoglobinuria.

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