Phillips Reflects on Lessons Learned With BTK Inhibitors in MCL

Welcome to OncLive On Air^®! I’m your host today, Jessica Hergert.

OncLive On Air^® is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive^® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we had the pleasure of speaking with Tycel Jovelle Phillips, MD, a clinical associate professor in the Division of Hematology and Oncology and Department of Internal Medicine at Rogel Cancer Center and Michigan Medicine, to discuss the clinical experience with BTK inhibitors in mantle cell lymphoma (MCL) since the approval of the first-in-class agent, ibrutinib (Imbruvica) in 2013.

In our exclusive interview, Phillips discussed the utility of ibrutinib, acalabrutinib (Calquence), and zanubrutinib (Brukinsa) in MCL, the impact of long-term follow-up data with ibrutinib, and findings from the phase 3 SYMPATICO trial that could shake up the treatment paradigm.

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