Inavolisib Expands the PIK3CA-Mutated Metastatic HR+ Breast Cancer Treatment Paradigm: With Virginia Kaklamani, MD, DSc

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by Genentech, we had the pleasure of speaking with Virginia Kaklamani, MD, DSc, about her advice regarding the use of inavolisib (Itovebi) for patients with hormone receptor (HR)–positive, PIK3CA-mutated, locally advanced or metastatic breast cancer. Dr Kaklamani is a professor of medicine in the Division of Hematology-Medical Oncology at The University of Texas Health Science Center San Antonio, as well as the leader of the breast cancer program at the Mays Cancer Center in San Antonio.

In our exclusive interview, Dr Kaklamani discussed the mechanism of action of inavolisib, the importance of the addition of this agent to the HR-positive metastatic breast cancer treatment paradigm, and considerations for early biomarker testing in patients with breast cancer.

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