Halmos on the AE Profiles of Dato-DXd and Other ADCs in NSCLC

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by AstraZeneca, we had the pleasure of speaking with Balazs Halmos, MD, MS, about adverse effect (AE) management with antibody-drug conjugates (ADCs) in non–small cell lung cancer (NSCLC). Dr Halmos is a professor in the Departments of Oncology and Medicine at the Albert Einstein College of Medicine, as well as associate director of Clinical Science at Montefiore Einstein Comprehensive Cancer Center in Bronx, New York.

In our exclusive interview, Dr Halmos discussed common AEs that are associated with the ADCs that are used in NSCLC; the safety profile of datopotamab deruxtecan, as seen in the phase 3 TROPION-Lung01 trial (NCT04656652) in patients with advanced or metastatic NSCLC; and ways to manage and mitigate these toxicities.

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