Gottschalk and Krenciute Discuss the Development of CAR T-cell Therapy in Pediatric Solid Tumors

May 25, 2023

Drs Gottschalk and Krenciute discuss the difficulties of translating successes with CAR T-cell therapy in adults to the pediatric population; ongoing research with investigational products that could reduce T-cell exhaustion, burnout, and the time from bench to bedside; and expectations for the future of cellular therapy in oncology.

Welcome to OncLive On Air^®! I’m your host today, Caroline Seymour.

OncLive On Air^® is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive^® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we had the pleasure of speaking with Stephen Gottschalk, MD, and Giedre Krenciute, PhD, of St. Jude Children’s Research Hospital, on the development of CAR T-cell therapy in pediatric patients with solid tumors.

Gottschalk is a member of the St. Jude faculty, chair of the Department of Bone Marrow Transplantation & Cellular Therapy, and Endowed Chair in Bone Marrow Transplantation & Cellular Therapy. Krenciute is an assistant member of the St. Jude faculty in the Department of Bone Marrow Transplant, Comprehensive Cancer Center, and St. Jude Graduate School of Biomedical Sciences in New York, New York.

In our exclusive interview, Drs Gottschalk and Krenciute discussed the difficulties of translating successes with CAR T-cell therapy in adults to the pediatric population; ongoing research with investigational products that could reduce T-cell exhaustion, burnout, and the time from bench to bedside; and expectations for the future of cellular therapy in oncology.

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