FDA Approval Insights: Tislelizumab Plus Chemo in Unresectable Metastatic ESCC: With Nataliya Uboha, MD, PhD

Welcome to OncLive On Air®! I’m your host today, Ashling Wahner.

OncLive On Air is a podcast from OncLive®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, supported by Beigene, we had the pleasure of speaking with Nataliya Uboha, MD, PhD, about the FDA approval of first-line tislelizumab-jsgr (Tevimbra) in combination with platinum-containing chemotherapy for the treatment of adult patients with unresectable or metastatic esophageal squamous cell carcinoma (ESCC) with a tumor PD-L1 expression of at least 1. Dr Uboha is a medical oncologist at the University of Wisconsin Health, as well as an associate professor and researcher in the Department of Medicine at the University of Wisconsin School of Medicine and Public Health in Madison.

In our exclusive interview, Dr Uboha discussed the significance of this approval, key efficacy and safety data from the pivotal phase 3 RATIONALE-306 trial (NCT03783442), and considerations for integrating this agent into the ESCC treatment paradigm.

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That’s all we have for today! Thank you for listening to this episode of OncLive On Air, supported by Beigene. Check back on Mondays and Thursdays for exclusive interviews with leading experts in the oncology field.

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