Dr. Shuo Ma on Non-Chemotherapy Regimens for Hematologic Malignancies

Shuo Ma, MD, PhD, assistant professor at Northwestern University in the Robert H. Lurie Comprehensive Cancer Center, discusses advances in non-chemotherapy regimens for patients with hematologic malignancies.

Rituximab in combination with bortezomib and rituximab in combination with lenalidomide have shown success for patients with relapsed/refractory indolent and mantle cell non-Hodgkin lymphoma . Both combinations provide a fairly high response rate in both the frontline setting and the relapse setting, says Ma.

B-cell receptor pathway inhibitors including ibrutinib and idelalisib also offer exciting benefits. Both have shown significant activity across many different forms of b-cell malignancies.

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