Dr. Ruff on Aflibercept in Elderly Patients With CRC

Paul Ruff, MD, director of Medical Oncology at the University of Witwatersrand, Johannesburg, South Africa, discusses treating elderly patients with colorectal cancer with aflibercept.

Ruff says physicians can use aflibercept to treat elderly patients with colorectal cancer as long as they are careful. Some side effects, such as dehydration, seem to be more severe in patients with colorectal cancer who are over the age of 65, Ruff says.

Ruff believes that most oncologists are aware of how to manage side effects from chemotherapy and anti-angiogenic agents. With good care management and proper awareness of its side effects, aflibercept can be used as a useful agent in the management of advanced colorectal cancer.