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Michael Morris, MD, a medical oncologist at Memorial Sloan Kettering Cancer Center, discusses the mechanism of action for radium-223 dichloride as a treatment for patients with prostate cancer.
Michael Morris, MD, a medical oncologist at Memorial Sloan Kettering Cancer Center, discusses the mechanism of action for radium-223 dichloride as a treatment for patients with prostate cancer.
The main idea behind a bone-targeting radiopharmaceutical such as radium-223, Morris explains, is that it targets the primary site of metastatic disease. Radium-223 delivers alpha-emitting radiation therapy to the bone, which is where much of prostate cancer localizes to.
Radium-223 has unique characteristics that minimize toxicity and maximizes treatment effect, Morris explains.
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