Dr. Ferguson on Minimally Invasive Vs Open Surgery for Radical Hysterectomy in Cervical Cancer

Sarah Ferguson, MD, FRCSC, associate professor of gynecologic oncology, University of Toronto, Princess Margaret Cancer Centre, discusses the rationale to conduct a population-based cohort study comparing the efficacy of minimally invasive surgery (MIS) versus open surgery for radical hysterectomy in women with cervical cancer.

The results of the LACC trial, a randomized international trial that compared MIS with open surgery for radical hysterectomy in women with cervical cancer, showed that mortality and recurrence rates were higher in patients who received MIS.

The results of the LACC trial were practice changing and caused a reconsideration of the benefits of MIS versus open surgery for radical hysterectomy. To increase the evidence and provide more real-world data, Ferguson conducted a cohort study in Ontario, Canada, making the same comparison.