Dr. Ciccolini on Dose Levels of Cetuximab in Head and Neck Cancer

Joseph Ciccolini, PhD, assistant professor in Pharmocokinetics, Aix-Marseille University, discusses dose levels of cetuximab (Erbitux) in patients with head and neck cancer.

The dose of cetuximab must be precise otherwise it will be difficult for a patient with head and neck cancer to see results, explains Ciccolini.

It needs to be ensured that the drug is at a certain level to exert constant pressure on the target. This makes dose de-escalation difficult with this drug, but it was the best way to see responses, states Ciccolini.