Dr. Choti on Pursuing Chemotherapy Following Tumor Resection in Advanced CRC

Michael A. Choti, MD, chief of surgery, Banner MD Anderson Cancer Center, discusses pursuing chemotherapy following tumor resection in advanced colorectal cancer (CRC).

Currently, no robust data have demonstrated the benefit of giving chemotherapy to patients with advanced-stage CRC after disease resection, says Choti. Conversely, in the early-stage setting, adjuvant chemotherapy is standard for patients with CRC as a means to prevent microscopic disease, Choti explains.

In the advanced-stage setting, some clinical trials have attempted to demonstrate benefit with chemotherapy in chemotherapy-naïve patients; however, it has been difficult to confirm clinical benefit with this approach, Choti concludes.