Dr. Bruix Discusses the Application of Regorafenib in HCC

Jordi Bruix, MD, head of the Barcelona Clinic Liver Cancer (BCLC) at University of Barcelona, discusses the application of regorafenib (Stivarga) in hepatocellular carcinoma as opposed to other tumor types.

Prior to its approval in HCC, regorafenib was approved in colorectal cancer and for patients with gastrointestinal stromal tumors (GIST). It was poorly tolerated in colorectal cancer, which made the oncology community question its application.

According to Bruix, it is imperative to consider the population in which this drug is applied. The population of patients with HCC that participated in RESORCE had progressed on sorafenib (Nexavar), adds Bruix, which is instrumental.