Christina M. Annunziata, MD, PhD, head, Translational Genomics Section, National Cancer Institute, discusses the phase II/III study of olaparib (Lynparza) and cediranib for patients with platinum-resistant ovarian cancer.

In the phase II setting, an initial signal of activity and safety will be investigated for each of the 4 arms, explains Annunziata. Currently, there are no data regarding these drugs in the platinum-resistant setting.

This study will then move on to the phase III setting to compare the combination with the standard of care.

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Dr. Annunziata on Olaparib and Cediranib Combination in Ovarian Cancer