Brody Previews ASH 2022 Data With Pirtobrutinib, CAR T-cell Therapy, and Glofitamab in MCL

December 8, 2022

Dr Brody previews mantle cell lymphoma data being presented at the 2022 ASH Annual Meeting and Exposition, including promising data on pirtobrutinib from the BRUIN trial, the potential for CAR T-cell therapy as evidenced in the ZUMA-2 trial, and how immunotherapies such as glofitamab are expanding the treatment paradigm.

Welcome to OncLive On Air^®! I’m your host today, Ashling Wahner.

OncLive On Air^® is a podcast from OncLive^®, which provides oncology professionals with the resources and information they need to provide the best patient care. In both digital and print formats, OncLive^® covers every angle of oncology practice, from new technology to treatment advances to important regulatory decisions.

In today’s episode, we had the pleasure of speaking with Joshua Brody, MD, the director of the Lymphoma Immunotherapy Program at the Tisch Cancer Institute at Mount Sinai and a faculty member of the Icahn Genomics Institute in New York, New York. Dr Brody joined us to preview mantle cell lymphoma (MCL) data being presented at the 2022 ASH Annual Meeting and Exposition.

In our exclusive interview, Dr Brody discussed promising data on pirtobrutinib (LOXO-305) in MCL from the phase 1/2 BRUIN trial (NCT03740529), the potential for CAR T-cell therapy in MCL as evidenced in the phase 2 ZUMA-2 trial (NCT02601313), and how immunotherapies such as glofitamab are expanding the treatment paradigm.

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