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Latest from UCLA Health Jonsson Comprehensive Cancer Center


Dr Hecht on Barriers to Enrollment into the BASECAMP-1 Study in Solid Tumors

September 26, 2023

J. Randolph (Randy) Hecht, MD, discusses barriers to enrollment in the observational BASECAMP-1 study and the phase 1/2 EVEREST-1 study, which will investigate HLA-A*02 as a target for the novel CAR T-cell therapy A2B530 in patients with solid tumors.

Dr Hecht on Barriers to CAR T-Cell Therapy Treatment in Solid Tumors

September 22, 2023

J. Randolph (Randy) Hecht, MD, discusses barriers to treatment with CAR T-cell therapy in patients with solid tumors, highlighting various efforts that investigators are spearheading to address these unmet needs.

Dr Callahan on Commonly Used Imaging Modalities in Breast Cancer

August 31, 2023

Rena D. Callahan, MD, discusses the range of metastatic imaging techniques available in breast cancer, the benefits of liquid biopsy, and the importance of looking for bone metastases in patients with metastatic breast cancer.

Dr Mead on the Use of Zanubrutinib vs Ibrutinib in MCL

August 25, 2023

Monica D. Mead, MD, discusses the efficacy and safety differences between the second-generation BTK inhibitor zanubrutinib and the first-generation BTK inhibitor ibrutinib in patients with mantle cell lymphoma.

Emerging Data Continue to Affect BTK Inhibitor Usage in Mantle Cell Lymphoma

August 21, 2023

Monica D. Mead, MD, discusses the evolving use of the BTK inhibitors in the treatment of patients with MCL, the factors for selecting between ibrutinib, zanubrutinib, and acalabrutinib, and unmet needs for patients with MCL.

Patient Profile 3: Metastatic HER2+ BC

August 17, 2023

Dr Kaklamani presents a profile of a patient with HER2+ breast cancer and liver metastases who had disease progression after first-line chemotherapy and a solitary new brain metastasis after second-line T-DM1.

Patient Profile 2: Early Stage HER2+/HR- BC

August 17, 2023

Melinda L. Telli, MD, presents a profile of a patient with early stage breast cancer with residual nodal disease after neoadjuvant chemotherapy and surgery, whose tumor was initially HER2+ but became triple-negative after treatment.